A carregar...
Cystine accumulation attenuates insulin release from the pancreatic β‐cell due to elevated oxidative stress and decreased ATP levels
KEY POINTS: In cystinosis, a lysosomal storage disorder, an altered redox state has been suggested as contributing to cellular dysfunction. Ctns gene knockdown in a pancreatic β‐cell line caused increased cystine levels. Attenuated nutrient stimulated insulin secretion was observed after Ctns knockd...
Na minha lista:
| Publicado no: | J Physiol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4667001/ https://ncbi.nlm.nih.gov/pubmed/26482480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271237 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|