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Cystine accumulation and clearance by normal and cystinotic leukocytes exposed to cystine dimethyl ester.

Upon exposure to 0.25 mM cystine dimethyl ester, normal and cystinotic leukocytes accumulate substantially more intracellular cystine than is present endogenously in cystinotic cells. Leukocytes loaded by exposure to cystine dimethyl ester may have abnormally lucent and distended lysosomes, and the...

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Détails bibliographiques
Auteurs principaux: Steinherz, R, Tietze, F, Gahl, W A, Triche, T J, Chiang, H, Modesti, A, Schulman, J D
Format: Artigo
Langue:Inglês
Publié: 1982
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC346689/
https://ncbi.nlm.nih.gov/pubmed/6956873
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