Cystine accumulation and clearance by normal and cystinotic leukocytes exposed to cystine dimethyl ester.

Upon exposure to 0.25 mM cystine dimethyl ester, normal and cystinotic leukocytes accumulate substantially more intracellular cystine than is present endogenously in cystinotic cells. Leukocytes loaded by exposure to cystine dimethyl ester may have abnormally lucent and distended lysosomes, and the...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Steinherz, R, Tietze, F, Gahl, W A, Triche, T J, Chiang, H, Modesti, A, Schulman, J D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1982
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346689/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6956873/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.14.4446
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