Nutritional Regulation of Insulin Secretion: Implications for Diabetes

Por Newsholme, Philip, Krause, Mauricio
Publicado em 2012

Mathematical Model of Metabolism and Electrophysiology of Amino Acid and Glucose Stimulated Insulin Secretion: In Vitro Validation Using a β-Cell Line

Por Salvucci, Manuela, Neufeld, Zoltan, Newsholme, Philip
Publicado em 2013

Amino acid supplementation and impact on immune function in the context of exercise

Por Cruzat, Vinicius Fernandes, Krause, Maurício, Newsholme, Philip
Publicado no J Int Soc Sports Nutr (2014)

Lysosomal cystine accumulation promotes mitochondrial depolarization and induction of redox‐sensitive genes in human kidney proximal tubular cells

Por Sumayao, Rodolfo, McEvoy, Bernadette, Newsholme, Philip, McMorrow, Tara
Publicado no J Physiol (2016)

Cancer stem cell metabolism: a potential target for cancer therapy

Por Deshmukh, Abhijeet, Deshpande, Kedar, Arfuso, Frank, Newsholme, Philip, Dharmarajan, Arun
Publicado no Mol Cancer (2016)

The Impact of Vitamin D Levels on Inflammatory Status: A Systematic Review of Immune Cell Studies

Por Calton, Emily K., Keane, Kevin N., Newsholme, Philip, Soares, Mario J.
Publicado no PLoS One (2015)

Cystine accumulation attenuates insulin release from the pancreatic β‐cell due to elevated oxidative stress and decreased ATP levels

Por McEvoy, Bernadette, Sumayao, Rodolfo, Slattery, Craig, McMorrow, Tara, Newsholme, Philip
Publicado no J Physiol (2015)

Overexpression of the malate–aspartate NADH shuttle member Aralar1 in the clonal β-cell line BRIN-BD11 enhances amino-acid-stimulated insulin secretion and cell metabolism

Por Bender, Katrin, Maechler, Pierre, McClenaghan, Neville H., Flatt, Peter R., Newsholme, Philip
Publicado em 2009

Wnt Antagonist Secreted Frizzled-Related Protein 4 Upregulates Adipogenic Differentiation in Human Adipose Tissue-Derived Mesenchymal Stem Cells

Por Visweswaran, Malini, Schiefer, Luca, Arfuso, Frank, Dilley, Rodney J., Newsholme, Philip, Dharmarajan, Arun
Publicado no PLoS One (2015)

Prevailing vitamin D status influences mitochondrial and glycolytic bioenergetics in peripheral blood mononuclear cells obtained from adults

Por Calton, Emily K., Keane, Kevin N., Soares, Mario J., Rowlands, Jordan, Newsholme, Philip
Publicado no Redox Biol (2016)

Arachidonic acid actions on functional integrity and attenuation of the negative effects of palmitic acid in a clonal pancreatic β-cell line

Por Keane, Deirdre C., Takahashi, Hilton K., Dhayal, Shalinee, Morgan, Noel G., Curi, Rui, Newsholme, Philip
Publicado em 2010

Molecular Events Linking Oxidative Stress and Inflammation to Insulin Resistance and β-Cell Dysfunction

Por Keane, Kevin Noel, Cruzat, Vinicius Fernandes, Carlessi, Rodrigo, de Bittencourt, Paulo Ivo Homem, Newsholme, Philip
Publicado no Oxid Med Cell Longev (2015)

Winter to summer change in vitamin D status reduces systemic inflammation and bioenergetic activity of human peripheral blood mononuclear cells

Por Calton, Emily K., Keane, Kevin N., Raizel, Raquel, Rowlands, Jordan, Soares, Mario J., Newsholme, Philip
Publicado no Redox Biol (2017)

Novel dehydroepiandrosterone troche supplementation improves the serum androgen profile of women undergoing in vitro fertilization

Por Keane, Kevin N, Hinchliffe, Peter M, Namdar, Navid, Conceicao, Jason L, Newsholme, Philip, Yovich, John L
Publicado no Drug Des Devel Ther (2015)

A proteomic analysis of the functional effects of fatty acids in NIH 3T3 fibroblasts

Por Magdalon, Juliana, Hatanaka, Elaine, Romanatto, Talita, Rodrigues, Hosana G, Kuwabara, Wilson MT, Scaife, Caitriona, Newsholme, Philip, Curi, Rui
Publicado em 2011

Divergence of intracellular and extracellular HSP72 in type 2 diabetes: does fat matter?

Por Rodrigues-Krause, Josianne, Krause, Mauricio, O’Hagan, C., De Vito, Giuseppe, Boreham, Colin, Murphy, Colin, Newsholme, Philip, Colleran, Gerard
Publicado em 2012

The Chaperone Balance Hypothesis: The Importance of the Extracellular to Intracellular HSP70 Ratio to Inflammation-Driven Type 2 Diabetes, the Effect of Exercise, and the Implicati...

Por Krause, Mauricio, Heck, Thiago Gomes, Bittencourt, Aline, Scomazzon, Sofia Pizzato, Newsholme, Philip, Curi, Rui, Homem de Bittencourt, Paulo Ivo
Publicado no Mediators Inflamm (2015)

The effect of cigarette smoking, alcohol consumption and fruit and vegetable consumption on IVF outcomes: a review and presentation of original data

Por Firns, Sarah, Cruzat, Vinicius Fernandes, Keane, Kevin Noel, Joesbury, Karen A., Lee, Andy H., Newsholme, Philip, Yovich, John L.
Publicado no Reprod Biol Endocrinol (2015)

Oleic, Linoleic and Linolenic Acids Increase ROS Production by Fibroblasts via NADPH Oxidase Activation

Por Hatanaka, Elaine, Dermargos, Alexandre, Hirata, Aparecida Emiko, Vinolo, Marco Aurélio Ramirez, Carpinelli, Angelo Rafael, Newsholme, Philip, Armelin, Hugo Aguirre, Curi, Rui
Publicado em 2013

Persistence of Inflammatory Response to Intense Exercise in Diabetic Rats

Por Bortolon, José Ricardo, Silva Junior, Antonio José de Almeida, Murata, Gilson Masahiro, Newsholme, Philip, Curi, Rui, Pithon-Curi, Tania Cristina, Hatanaka, Elaine
Publicado em 2012