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The Role of Cystinosin in the Intermediary Thiol Metabolism and Redox Homeostasis in Kidney Proximal Tubular Cells

Cystinosin is a lysosomal transmembrane protein which facilitates transport of the disulphide amino acid cystine (CySS) from the lysosomes of the cell. This protein is encoded by the CTNS gene which is defective in the lysosomal storage disorder, cystinosis. Because of the apparent involvement of cy...

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Dettagli Bibliografici
Pubblicato in:Antioxidants (Basel)
Autori principali: Sumayao, Rodolfo, Newsholme, Philip, McMorrow, Tara
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315507/
https://ncbi.nlm.nih.gov/pubmed/30513914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox7120179
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