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Tacrolimus Modulates TGF-β Signaling to Induce Epithelial-Mesenchymal Transition in Human Renal Proximal Tubule Epithelial Cells

Epithelial-mesenchymal transition (EMT), a process which describes the trans-differentiation of epithelial cells into motile mesenchymal cells, is pivotal in stem cell behavior, development and wound healing, as well as contributing to disease processes including fibrosis and cancer progression. Mai...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Bennett, Jason, Cassidy, Hilary, Slattery, Craig, Ryan, Michael P., McMorrow, Tara
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882479/
https://ncbi.nlm.nih.gov/pubmed/27128949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm5050050
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