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Tacrolimus Modulates TGF-β Signaling to Induce Epithelial-Mesenchymal Transition in Human Renal Proximal Tubule Epithelial Cells

Epithelial-mesenchymal transition (EMT), a process which describes the trans-differentiation of epithelial cells into motile mesenchymal cells, is pivotal in stem cell behavior, development and wound healing, as well as contributing to disease processes including fibrosis and cancer progression. Mai...

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書目詳細資料
發表在:J Clin Med
Main Authors: Bennett, Jason, Cassidy, Hilary, Slattery, Craig, Ryan, Michael P., McMorrow, Tara
格式: Artigo
語言:Inglês
出版: MDPI 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882479/
https://ncbi.nlm.nih.gov/pubmed/27128949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm5050050
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