Glycine N-Methyltransferase and Regulation of S-Adenosylmethionine Levels

Por Luka, Zigmund, Mudd, S. Harvey, Wagner, Conrad
Publicado em 2009

Acetylation of N-terminal valine of glycine N-methyltransferase affects enzyme inhibition by folate

Por Luka, Zigmund, Loukachevitch, Lioudmila V., Wagner, Conrad
Publicado em 2008

A Glycine N-methyltransferase knockout mouse model for humans with deficiency of this enzyme

Por Luka, Zigmund, Capdevila, Antonieta, Mato, José M., Wagner, C.
Publicado em 2006

Destabilization of human glycine N-methyltransferase by H176N mutation

Por Luka, Zigmund, Pakhomova, Svetlana, Luka, Yury, Newcomer, Marcia E., Wagner, Conrad
Publicado em 2007

Histone demethylase LSD1 is a folate-binding protein

Por Luka, Zigmund, Moss, Frank, Loukachevitch, Lioudmila V., Bornhop, Darryl J., Wagner, Conrad
Publicado em 2011

Differences in folate-protein interactions result in differing inhibition of native rat liver and recombinant glycine N-methyltransferase by 5-methyltetrahydrofolate

Por Luka, Zigmund, Pakhomova, Svetlana, Loukachevitch, Lioudmila V., Newcomer, Marcia E., Wagner, Conrad
Publicado em 2011

Folate in demethylation: the crystal structure of the rat dimethylglycine dehydrogenase complexed with tetrahydrofolate

Por Luka, Zigmund, Pakhomova, Svetlana, Loukachevitch, Lioudmila V., Newcomer, Marcia E., Wagner, Conrad
Publicado em 2014

Folate deficiency affects histone methylation

Por Garcia, Benjamin A., Luka, Zigmund, Loukachevitch, Lioudmila V., Bhanu, Natarajan V., Wagner, Conrad
Publicado no Med Hypotheses (2016)

G-quadruplex RNA binding and recognition by the lysine-specific histone demethylase-1 enzyme

Por Hirschi, Alexander, Martin, William J., Luka, Zigmund, Loukachevitch, Lioudmila V., Reiter, Nicholas J.
Publicado no RNA (2016)

Crystal structure of the histone lysine specific demethylase LSD1 complexed with tetrahydrofolate

Por Luka, Zigmund, Pakhomova, Svetlana, Loukachevitch, Lioudmila V, Calcutt, M Wade, Newcomer, Marcia E, Wagner, Conrad
Publicado em 2014

Two patients with hepatic mtDNA depletion syndromes and marked elevations of S-adenosylmethionine and methionine

Por Mudd, S. Harvey, Wagner, Conrad, Luka, Zigmund, Stabler, Sally P., Allen, Robert H., Schroer, Richard, Wood, Timothy, Wang, Jing, Wong, Lee-Jun
Publicado em 2011

Changes in S-adenosylmethionine and GSH homeostasis during endotoxemia in mice

Por Ko, Kwangsuk, Yang, Heping, Noureddin, Mazen, Iglesia-Ara, Ainhoa, Xia, Meng, Wagner, Conrad, Luka, Zigmund, Mato, José M, Lu, Shelly C
Publicado no Lab Invest (2008)

INHIBITION OF NK CELLS PROTECTS THE LIVER AGAINST ACUTE INJURY IN THE ABSENCE OF GNMT

Por Gomez-Santos, Laura, Luka, Zigmund, Wagner, Conrad, Fernandez-Alvarez, Sara, Lu, Shelly C, Mato, Jose M, Martinez-Chantar, Maria L, Beraza, Naiara
Publicado em 2012

Identification of phosphorylation sites in glycine N-methyltransferase from rat liver

Por Luka, Zigmund, Ham, Amy-Joan L., Norris, Jeremy L., Yeo, Eui-Ju, Yermalitsky, Valery, Glenn, Byron, Caprioli, Richard M., Liebler, Daniel C., Wagner, Conrad
Publicado em 2006

Serum Methionine Metabolites Are Risk Factors for Metastatic Prostate Cancer Progression

Por Stabler, Sally, Koyama, Tatsuki, Zhao, Zhiguo, Martinez-Ferrer, Magaly, Allen, Robert H., Luka, Zigmund, Loukachevitch, Lioudmila V., Clark, Peter E., Wagner, Conrad, Bhowmick, Neil A.
Publicado em 2011

High-frequency ultrasound imaging for longitudinal evaluation of non-alcoholic fatty liver disease progression in mice

Por Fernández-Domínguez, Itziar, Echevarria-Uraga, J Javier, Gómez, Nieves, Luka, Zigmund, Wagner, Conrad, Lu, Shelly C, Mato, José M, Martínez-Chantar, Maria L, Rodríguez-Cuesta, Juan
Publicado em 2011

Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples

Por Conde-Vancells, Javier, Rodriguez-Suarez, Eva, Gonzalez, Esperanza, Berisa, Agustin, Gil, David, Embade, Nieves, Valle, Mikel, Luka, Zigmund, Elortza, Felix, Wagner, Conrad, Lu, Shelly C., Mato, Jose M., Falcon-Perez, Juan M.
Publicado em 2010

Glycine N-methyltransferase expression in the hippocampus and its role in neurogenesis and cognitive performance

Por Carrasco, Manuel, Rabaneda, Luis G., Murillo-Carretero, Maribel, Ortega-Martínez, Sylvia, Martínez-Chantar, María L., Woodhoo, Ashwin, Luka, Zigmund, Wagner, Conrad, Lu, Shelly C., Mato, José M., Micó, Juan A., Castro, Carmen
Publicado em 2014

TRAIL-producing NK cells contribute to liver injury and related fibrogenesis in the context of GNMT deficiency

Por Fernández-Álvarez, Sara, Juan, Virginia Gutiérrez-de, Zubiete-Franco, Imanol, Barbier-Torres, Lucia, Lahoz, Agustín, Parés, Albert, Luka, Zigmund, Wagner, Conrad, Lu, Shelly C., Mato, José M., Martínez-Chantar, María Luz, Beraza, Naiara
Publicado no Lab Invest (2014)

Impaired Liver Regeneration in Mice Lacking Glycine N-Methyltransferase

Por Varela-Rey, Marta, Fernández-Ramos, David, Martínez-López, Nuria, Embade, Nieves, Gómez-Santos, Laura, Beraza, Naiara, Vázquez-Chantada, Mercedes, Rodríguez, Juan, Luka, Zigmund, Wagner, Conrad, Lu, Shelly C, Martínez-Chantar, M Luz, Mato, José M
Publicado em 2009