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Crystal structure of the histone lysine specific demethylase LSD1 complexed with tetrahydrofolate
An important epigenetic modification is the methylation/demethylation of histone lysine residues. The first histone demethylase to be discovered was a lysine-specific demethylase 1, LSD1, a flavin containing enzyme which carries out the demethylation of di- and monomethyllysine 4 in histone H3. The...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4088983/ https://ncbi.nlm.nih.gov/pubmed/24715612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2469 |
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