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Folate in demethylation: the crystal structure of the rat dimethylglycine dehydrogenase complexed with tetrahydrofolate

Dimethylglycine dehydrogenase (DMGDH) is a mammalian mitochondrial enzyme which plays an important role in the utilization of methyl groups derived from choline. DMGDH is a flavin containing enzyme which catalyzes the oxidative demethylation of dimethylglycine in vitro with the formation of sarcosin...

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Detalhes bibliográficos
Main Authors: Luka, Zigmund, Pakhomova, Svetlana, Loukachevitch, Lioudmila V., Newcomer, Marcia E., Wagner, Conrad
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113215/
https://ncbi.nlm.nih.gov/pubmed/24858690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.05.064
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