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Acetylation of N-terminal valine of glycine N-methyltransferase affects enzyme inhibition by folate
Native liver glycine N-methyltransferase is N-acetylated while the recombinant enzyme is not. We show here that acetylation of the N-terminal valine affects several of kinetic parameters of the enzyme. Glycine N-methyltransferase is a regulatory enzyme mediating the availability of methyl groups by...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2576408/ https://ncbi.nlm.nih.gov/pubmed/18501206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2008.04.016 |
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