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Acetylation of N-terminal valine of glycine N-methyltransferase affects enzyme inhibition by folate

Native liver glycine N-methyltransferase is N-acetylated while the recombinant enzyme is not. We show here that acetylation of the N-terminal valine affects several of kinetic parameters of the enzyme. Glycine N-methyltransferase is a regulatory enzyme mediating the availability of methyl groups by...

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Bibliografiska uppgifter
Huvudupphovsmän: Luka, Zigmund, Loukachevitch, Lioudmila V., Wagner, Conrad
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576408/
https://ncbi.nlm.nih.gov/pubmed/18501206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2008.04.016
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