CCAAT/Enhancer-binding Protein α (C/EBPα) and Hepatocyte Nuclear Factor 4α (HNF4α) Synergistically Cooperate with Constitutive Androstane Receptor to Transactivate the Human Cytoch...

por Benet, Marta, Lahoz, Agustín, Guzmán, Carla, Castell, José V., Jover, Ramiro
Publicado 2010

Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method

por García-Cañaveras, Juan C., Donato, M. Teresa, Castell, José V., Lahoz, Agustín
Publicado 2012

A metabolomics cell-based approach for anticipating and investigating drug-induced liver injury

por García- Cañaveras, Juan Carlos, Castell, José V., Donato, M. Teresa, Lahoz, Agustín
Publicado en Sci Rep (2016)

Direct conversion of human fibroblast to hepatocytes using a single inducible polycistronic vector

por Ballester, Maria, Bolonio, Miguel, Santamaria, Ramon, Castell, José V., Ribes-Koninckx, Carmen, Bort, Roque
Publicado en Stem Cell Res Ther (2019)

Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury

por Tolosa, Laia, Jiménez, Nuria, Pérez, Gabriela, Castell, José V., Gómez-Lechón, M. José, Donato, M. Teresa
Publicado en Arch Toxicol (2017)

Silencing of hepatic fate-conversion factors induce tumorigenesis in reprogrammed hepatic progenitor-like cells

por Serrano, Felipe, García-Bravo, Maria, Blazquez, Marina, Torres, Josema, Castell, Jose V., Segovia, Jose C., Bort, Roque
Publicado en Stem Cell Res Ther (2016)

Monitoring of system conditioning after blank injections in untargeted UPLC-MS metabolomic analysis

por Martínez-Sena, Teresa, Luongo, Giovanna, Sanjuan-Herráez, Daniel, Castell, José V., Vento, Máximo, Quintás, Guillermo, Kuligowski, Julia
Publicado en Sci Rep (2019)

A Physiology-Based Model of Human Bile Acid Metabolism for Predicting Bile Acid Tissue Levels After Drug Administration in Healthy Subjects and BRIC Type 2 Patients

por Baier, Vanessa, Cordes, Henrik, Thiel, Christoph, Castell, José V., Neumann, Ulf P., Blank, Lars M., Kuepfer, Lars
Publicado en Front Physiol (2019)

Interaction between Hhex and SOX13 Modulates Wnt/TCF Activity

por Marfil, Vanessa, Moya, Marta, Pierreux, Christophe E., Castell, Jose V., Lemaigre, Frédéric P., Real, Francisco X., Bort, Roque
Publicado 2010

New microRNA Biomarkers for Drug-Induced Steatosis and Their Potential to Predict the Contribution of Drugs to Non-alcoholic Fatty Liver Disease

por López-Riera, Mireia, Conde, Isabel, Tolosa, Laia, Zaragoza, Ángela, Castell, José V., Gómez-Lechón, María J., Jover, Ramiro
Publicado en Front Pharmacol (2017)

Non-invasive prediction of NAFLD severity: a comprehensive, independent validation of previously postulated serum microRNA biomarkers

por López-Riera, Mireia, Conde, Isabel, Quintas, Guillermo, Pedrola, Laia, Zaragoza, Ángela, Perez-Rojas, Judith, Salcedo, Mario, Benlloch, Salvador, Castell, José V., Jover, Ramiro
Publicado en Sci Rep (2018)

Comparing Targeted vs. Untargeted MS(2) Data-Dependent Acquisition for Peak Annotation in LC–MS Metabolomics

por Ten-Doménech, Isabel, Martínez-Sena, Teresa, Moreno-Torres, Marta, Sanjuan-Herráez, Juan Daniel, Castell, José V., Parra-Llorca, Anna, Vento, Máximo, Quintás, Guillermo, Kuligowski, Julia
Publicado en Metabolites (2020)

The in vitro assessment of the toxicity of volatile, oxidisable, redox-cycling compounds: phenols as an example

por Tolosa, Laia, Martínez-Sena, Teresa, Schimming, Johannes P., Moro, Erika, Escher, Sylvia E., ter Braak, Bas, van der Water, Bob, Miranda, M. A., van Vugt-Lussenburg, Barbara M. A., Castell, José V.
Publicado en Arch Toxicol (2021)

Comparing in vitro human liver models to in vivo human liver using RNA-Seq

por Gupta, Rajinder, Schrooders, Yannick, Hauser, Duncan, van Herwijnen, Marcel, Albrecht, Wiebke, ter Braak, Bas, Brecklinghaus, Tim, Castell, Jose V., Elenschneider, Leroy, Escher, Sylvia, Guye, Patrick, Hengstler, Jan G., Ghallab, Ahmed, Hansen, Tanja, Leist, Marcel, Maclennan, Richard, Moritz, Wolfgang, Tolosa, Laia, Tricot, Tine, Verfaillie, Catherine, Walker, Paul, van de Water, Bob, Kleinjans, Jos, Caiment, Florian
Publicado en Arch Toxicol (2020)