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Direct conversion of human fibroblast to hepatocytes using a single inducible polycistronic vector
BACKGROUND: Human fibroblasts can be reprogrammed into induced hepatocyte-like cells through the expression of a set of transcription factors. Although the generation of induced hepatocyte-like cells by HNF4A, HNF1A, and FOXA3 expression has proven to be a robust experimental strategy, using multipl...
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| Publicado no: | Stem Cell Res Ther |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6829923/ https://ncbi.nlm.nih.gov/pubmed/31685034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1416-5 |
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