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Direct conversion of porcine primary fibroblasts into hepatocyte-like cells

The pig is an important model organism for biomedical research, mainly due to its extensive genetic, physiological and anatomical similarities with humans. Until date, direct conversion of somatic cells into hepatocyte-like cells (iHeps) has only been achieved in rodents and human cells. Here, we em...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fráguas-Eggenschwiler, Mariane, Eggenschwiler, Reto, Söllner, Jenny-Helena, Cortnumme, Leon, Vondran, Florian W. R., Cantz, Tobias, Ott, Michael, Niemann, Heiner
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085017/
https://ncbi.nlm.nih.gov/pubmed/33927320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88727-1
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