Dynamic Nature of presenilin1/γ-Secretase: Implication for Alzheimer’s Disease Pathogenesis

Yazar: Zoltowska, Katarzyna Marta, Berezovska, Oksana
Yayımlandı Mol Neurobiol (2017)

Interrelationship between Changes in the Amyloid β 42/40 Ratio and Presenilin 1 Conformation

Yazar: Zoltowska, Katarzyna Marta, Maesako, Masato, Berezovska, Oksana
Yayımlandı Mol Med (2016)

Synapsin 1 promotes Aβ generation via BACE1 modulation

Yazar: Maesako, Masato, Zoltowska, Katarzyna M., Berezovska, Oksana
Yayımlandı PLoS One (2019)

Novel interaction between Alzheimer’s disease-related protein presenilin 1 and glutamate transporter 1

Yazar: Zoltowska, Katarzyna Marta, Maesako, Masato, Meier, Joshua, Berezovska, Oksana
Yayımlandı Sci Rep (2018)

Visualizing Interaction of Proteins relevant to Alzheimer’s Disease in intact Cells

Yazar: Thomas, Anne V., Berezovska, Oksana, Hyman, Bradley T., von Arnim, Christine A. F.
Baskı/Yayın Bilgisi 2008

Reciprocal relationship between APP positioning relative to the membrane and PS1 conformation

Yazar: Uemura, Kengo, Farner, Katherine C, Nasser-Ghodsi, Navine, Jones, Phill, Berezovska, Oksana
Baskı/Yayın Bilgisi 2011

Synaptotagmins interact with APP and promote Aβ generation

Yazar: Gautam, Vivek, D’Avanzo, Carla, Berezovska, Oksana, Tanzi, Rudolph E., Kovacs, Dora M.
Yayımlandı Mol Neurodegener (2015)

Oxidative stress and lipid peroxidation are upstream of amyloid pathology

Yazar: Arimon, Muriel, Takeda, Shuko, Post, Kathryn L., Svirsky, Sarah, Hyman, Bradley T., Berezovska, Oksana
Yayımlandı Neurobiol Dis (2015)

Amyloid Precursor Protein Associates with a Nicastrin-Dependent Docking Site on the Presenilin 1–γ-Secretase Complex in Cells Demonstrated by Fluorescence Lifetime Imaging

Yazar: Berezovska, Oksana, Ramdya, Pavan, Skoch, Jesse, Wolfe, Michael S., Bacskai, Brian J., Hyman, Bradley T.
Yayımlandı J Neurosci (2003)

Visualization of PS/γ-Secretase Activity in Living Cells

Yazar: Maesako, Masato, Sekula, Nicole M., Aristarkhova, Anna, Feschenko, Polina, Anderson, Lauren C., Berezovska, Oksana
Yayımlandı iScience (2020)

Limited Substrate Specificity of PS/γ-Secretase Is Supported by Novel Multiplexed FRET Analysis in Live Cells

Yazar: Houser, Mei C. Q., Turchyna, Yuliia, Perrin, Florian, Chibnik, Lori, Berezovska, Oksana, Maesako, Masato
Yayımlandı Biosensors (Basel) (2021)

Presenilin 1 increases association with synaptotagmin 1 during normal aging

Yazar: Keller, Laura J., Sekula, Nicole M., Svirsky, Sarah, Maesako, Masato, Zoltowska, Katarzyna M., Berezovska, Oksana
Yayımlandı Neurobiol Aging (2019)

A Novel NIR-FRET Biosensor for Reporting PS/γ-Secretase Activity in Live Cells

Yazar: Houser, Mei CQ, Hou, Steven S, Perrin, Florian, Turchyna, Yuliia, Bacskai, Brian J, Berezovska, Oksana, Maesako, Masato
Yayımlandı Sensors (Basel) (2020)

PRESENILIN-1 ADOPTS PATHOGENIC CONFORMATION IN NORMAL AGING AND IN SPORADIC ALZHEIMER’S DISEASE

Yazar: Wahlster, Lara, Arimon, Muriel, Nasser-Ghodsi, Navine, Post, Kathryn Leigh, Serrano-Pozo, Alberto, Uemura, Kengo, Berezovska, Oksana
Baskı/Yayın Bilgisi 2012

CHIP Targets Toxic α-Synuclein Oligomers for Degradation

Yazar: Tetzlaff, Julie E., Putcha, Preeti, Outeiro, Tiago F., Ivanov, Alexander, Berezovska, Oksana, Hyman, Bradley T., McLean, Pamela J.
Baskı/Yayın Bilgisi 2008

Dynamic presenilin 1 and synaptotagmin 1 interaction modulates exocytosis and amyloid β production

Yazar: Zoltowska, Katarzyna Marta, Maesako, Masato, Lushnikova, Iryna, Takeda, Shuko, Keller, Laura J., Skibo, Galina, Hyman, Bradley T., Berezovska, Oksana
Yayımlandı Mol Neurodegener (2017)

Familial Alzheimer's Disease Presenilin 1 Mutations Cause Alterations in the Conformation of Presenilin and Interactions with Amyloid Precursor Protein

Yazar: Berezovska, Oksana, Lleo, Alberto, Herl, Lauren D., Frosch, Matthew P., Stern, Edward A., Bacskai, Brian J., Hyman, Bradley T.
Yayımlandı J Neurosci (2005)

Substrate docking to γ-secretase allows access of γ-secretase modulators to an allosteric site

Yazar: Uemura, Kengo, Farner, Katherine C., Hashimoto, Tadafumi, Nasser-Ghodsi, Navine, Wolfe, Michael S., Koo, Edward H., Hyman, Bradley T., Berezovska, Oksana
Baskı/Yayın Bilgisi 2010

Neuronal Activity and Secreted Amyloid β Lead to Altered Amyloid β Precursor Protein and Presenilin 1 Interactions

Yazar: Li, Xuejing, Uemura, Kengo, Hashimoto, Tadafumi, Arimon, Muriel, Lill, Christina M., Palazzolo, Isabella, Krainc, Dimitri, Hyman, Bradley T., Berezovska, Oksana
Baskı/Yayın Bilgisi 2012

Convergence of pathology in dementia with Lewy bodies and Alzheimer’s disease: a role for the novel interaction of alpha-synuclein and presenilin 1 in disease

Yazar: Winslow, Ashley R., Moussaud, Simon, Zhu, Liya, Post, Katherine L., Dickson, Dennis W., Berezovska, Oksana, McLean, Pamela J.
Baskı/Yayın Bilgisi 2014