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Synapsin 1 promotes Aβ generation via BACE1 modulation

It has been revealed that β-amyloid (Aβ) is generated and released from the presynaptic terminals in activity-dependent manner. However, molecules modulating the presynaptic Aβ generation remain elusive. Here we test the hypothesis that Synapsin 1 (Syn1) may acts as a modulator of the Aβ production....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Maesako, Masato, Zoltowska, Katarzyna M., Berezovska, Oksana
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907790/
https://ncbi.nlm.nih.gov/pubmed/31830091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226368
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