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Synapsin 1 promotes Aβ generation via BACE1 modulation
It has been revealed that β-amyloid (Aβ) is generated and released from the presynaptic terminals in activity-dependent manner. However, molecules modulating the presynaptic Aβ generation remain elusive. Here we test the hypothesis that Synapsin 1 (Syn1) may acts as a modulator of the Aβ production....
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| Publicado no: | PLoS One |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6907790/ https://ncbi.nlm.nih.gov/pubmed/31830091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226368 |
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