The effect of BACE1-AS on β-amyloid generation by regulating BACE1 mRNA expression

BACKGROUND: The BACE1 antisense transcript (BACE1-AS) is a conserved long noncoding RNA (lncRNA). The level of BACE1-AS is significantly increased and the level of the BACE1 mRNA is slightly increased in subjects with AD. BACE1-AS exerts a significant moderating effect on the expression of the BACE1...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Mol Biol
Auteurs principaux: Li, Fan, Wang, Yun, Yang, Hui, Xu, Yingying, Zhou, Xiaoyan, Zhang, Xiao, Xie, Zhaohong, Bi, Jianzhong
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771094/
https://ncbi.nlm.nih.gov/pubmed/31570097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-019-0140-0
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