Dynamic Nature of presenilin1/γ-Secretase: Implication for Alzheimer’s Disease Pathogenesis

av Zoltowska, Katarzyna Marta, Berezovska, Oksana
I publikationen Mol Neurobiol (2017)

Interrelationship between Changes in the Amyloid β 42/40 Ratio and Presenilin 1 Conformation

av Zoltowska, Katarzyna Marta, Maesako, Masato, Berezovska, Oksana
I publikationen Mol Med (2016)

Synapsin 1 promotes Aβ generation via BACE1 modulation

av Maesako, Masato, Zoltowska, Katarzyna M., Berezovska, Oksana
I publikationen PLoS One (2019)

Novel interaction between Alzheimer’s disease-related protein presenilin 1 and glutamate transporter 1

av Zoltowska, Katarzyna Marta, Maesako, Masato, Meier, Joshua, Berezovska, Oksana
I publikationen Sci Rep (2018)

Visualizing Interaction of Proteins relevant to Alzheimer’s Disease in intact Cells

av Thomas, Anne V., Berezovska, Oksana, Hyman, Bradley T., von Arnim, Christine A. F.
Publicerad 2008

Reciprocal relationship between APP positioning relative to the membrane and PS1 conformation

av Uemura, Kengo, Farner, Katherine C, Nasser-Ghodsi, Navine, Jones, Phill, Berezovska, Oksana
Publicerad 2011

Synaptotagmins interact with APP and promote Aβ generation

av Gautam, Vivek, D’Avanzo, Carla, Berezovska, Oksana, Tanzi, Rudolph E., Kovacs, Dora M.
I publikationen Mol Neurodegener (2015)

Oxidative stress and lipid peroxidation are upstream of amyloid pathology

av Arimon, Muriel, Takeda, Shuko, Post, Kathryn L., Svirsky, Sarah, Hyman, Bradley T., Berezovska, Oksana
I publikationen Neurobiol Dis (2015)

Amyloid Precursor Protein Associates with a Nicastrin-Dependent Docking Site on the Presenilin 1–γ-Secretase Complex in Cells Demonstrated by Fluorescence Lifetime Imaging

av Berezovska, Oksana, Ramdya, Pavan, Skoch, Jesse, Wolfe, Michael S., Bacskai, Brian J., Hyman, Bradley T.
I publikationen J Neurosci (2003)

Visualization of PS/γ-Secretase Activity in Living Cells

av Maesako, Masato, Sekula, Nicole M., Aristarkhova, Anna, Feschenko, Polina, Anderson, Lauren C., Berezovska, Oksana
I publikationen iScience (2020)

Limited Substrate Specificity of PS/γ-Secretase Is Supported by Novel Multiplexed FRET Analysis in Live Cells

av Houser, Mei C. Q., Turchyna, Yuliia, Perrin, Florian, Chibnik, Lori, Berezovska, Oksana, Maesako, Masato
I publikationen Biosensors (Basel) (2021)

Presenilin 1 increases association with synaptotagmin 1 during normal aging

av Keller, Laura J., Sekula, Nicole M., Svirsky, Sarah, Maesako, Masato, Zoltowska, Katarzyna M., Berezovska, Oksana
I publikationen Neurobiol Aging (2019)

A Novel NIR-FRET Biosensor for Reporting PS/γ-Secretase Activity in Live Cells

av Houser, Mei CQ, Hou, Steven S, Perrin, Florian, Turchyna, Yuliia, Bacskai, Brian J, Berezovska, Oksana, Maesako, Masato
I publikationen Sensors (Basel) (2020)

PRESENILIN-1 ADOPTS PATHOGENIC CONFORMATION IN NORMAL AGING AND IN SPORADIC ALZHEIMER’S DISEASE

av Wahlster, Lara, Arimon, Muriel, Nasser-Ghodsi, Navine, Post, Kathryn Leigh, Serrano-Pozo, Alberto, Uemura, Kengo, Berezovska, Oksana
Publicerad 2012

CHIP Targets Toxic α-Synuclein Oligomers for Degradation

av Tetzlaff, Julie E., Putcha, Preeti, Outeiro, Tiago F., Ivanov, Alexander, Berezovska, Oksana, Hyman, Bradley T., McLean, Pamela J.
Publicerad 2008

Dynamic presenilin 1 and synaptotagmin 1 interaction modulates exocytosis and amyloid β production

av Zoltowska, Katarzyna Marta, Maesako, Masato, Lushnikova, Iryna, Takeda, Shuko, Keller, Laura J., Skibo, Galina, Hyman, Bradley T., Berezovska, Oksana
I publikationen Mol Neurodegener (2017)

Familial Alzheimer's Disease Presenilin 1 Mutations Cause Alterations in the Conformation of Presenilin and Interactions with Amyloid Precursor Protein

av Berezovska, Oksana, Lleo, Alberto, Herl, Lauren D., Frosch, Matthew P., Stern, Edward A., Bacskai, Brian J., Hyman, Bradley T.
I publikationen J Neurosci (2005)

Substrate docking to γ-secretase allows access of γ-secretase modulators to an allosteric site

av Uemura, Kengo, Farner, Katherine C., Hashimoto, Tadafumi, Nasser-Ghodsi, Navine, Wolfe, Michael S., Koo, Edward H., Hyman, Bradley T., Berezovska, Oksana
Publicerad 2010

Neuronal Activity and Secreted Amyloid β Lead to Altered Amyloid β Precursor Protein and Presenilin 1 Interactions

av Li, Xuejing, Uemura, Kengo, Hashimoto, Tadafumi, Arimon, Muriel, Lill, Christina M., Palazzolo, Isabella, Krainc, Dimitri, Hyman, Bradley T., Berezovska, Oksana
Publicerad 2012

Convergence of pathology in dementia with Lewy bodies and Alzheimer’s disease: a role for the novel interaction of alpha-synuclein and presenilin 1 in disease

av Winslow, Ashley R., Moussaud, Simon, Zhu, Liya, Post, Katherine L., Dickson, Dennis W., Berezovska, Oksana, McLean, Pamela J.
Publicerad 2014