Domain Motion in Cytochrome P450 Reductase: CONFORMATIONAL EQUILIBRIA REVEALED BY NMR AND SMALL-ANGLE X-RAY SCATTERING

Por Ellis, Jacqueline, Gutierrez, Aldo, Barsukov, Igor L., Huang, Wei-Cheng, Grossmann, J. Günter, Roberts, Gordon C. K.
Publicado em 2009

The domain structure of talin: Residues 1815–1973 form a five-helix bundle containing a cryptic vinculin-binding site

Por Goult, Benjamin T., Gingras, Alexandre R., Bate, Neil, Barsukov, Igor L., Critchley, David R., Roberts, Gordon C.K.
Publicado em 2010

A Conserved Lipid-binding Loop in the Kindlin FERM F1 Domain Is Required for Kindlin-mediated αIIbβ3 Integrin Coactivation

Por Bouaouina, Mohamed, Goult, Benjamin T., Huet-Calderwood, Clotilde, Bate, Neil, Brahme, Nina N., Barsukov, Igor L., Critchley, David R., Calderwood, David A.
Publicado em 2012

LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex

Por Zacharchenko, Thomas, Qian, Xiaolan, Goult, Benjamin T., Jethwa, Devina, Almeida, Teresa B., Ballestrem, Christoph, Critchley, David R., Lowy, Douglas R., Barsukov, Igor L.
Publicado no Structure (2016)

The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain

Por Elliott, Paul R., Goult, Benjamin T., Kopp, Petra M., Bate, Neil, Grossmann, J. Günter, Roberts, Gordon C.K., Critchley, David R., Barsukov, Igor L.
Publicado em 2010

Central Region of Talin Has a Unique Fold That Binds Vinculin and Actin

Por Gingras, Alexandre R., Bate, Neil, Goult, Benjamin T., Patel, Bipin, Kopp, Petra M., Emsley, Jonas, Barsukov, Igor L., Roberts, Gordon C. K., Critchley, David R.
Publicado em 2010

Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: Implications for talin activation

Por Goult, Benjamin T., Xu, Xiao-Ping, Gingras, Alexandre R., Swift, Mark, Patel, Bipin, Bate, Neil, Kopp, Petra M., Barsukov, Igor L., Critchley, David R., Volkmann, Niels, Hanein, Dorit
Publicado em 2013

Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle

Por Papagrigoriou, Evangelos, Gingras, Alexandre R, Barsukov, Igor L, Bate, Neil, Fillingham, Ian J, Patel, Bipin, Frank, Ronald, Ziegler, Wolfgang H, Roberts, Gordon CK, Critchley, David R, Emsley, Jonas
Publicado em 2004

The Structure of an Interdomain Complex That Regulates Talin Activity

Por Goult, Benjamin T., Bate, Neil, Anthis, Nicholas J., Wegener, Kate L., Gingras, Alexandre R., Patel, Bipin, Barsukov, Igor L., Campbell, Iain D., Roberts, Gordon C. K., Critchley, David R.
Publicado em 2009

The Structure of the N-Terminus of Kindlin-1: A Domain Important for αIIbβ3 Integrin Activation

Por Goult, Benjamin T., Bouaouina, Mohamed, Harburger, David S., Bate, Neil, Patel, Bipin, Anthis, Nicholas J., Campbell, Iain D., Calderwood, David A., Barsukov, Igor L., Roberts, Gordon C., Critchley, David R.
Publicado em 2009

RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover

Por Goult, Benjamin T., Zacharchenko, Thomas, Bate, Neil, Tsang, Ricky, Hey, Fiona, Gingras, Alexandre R., Elliott, Paul R., Roberts, Gordon C. K., Ballestrem, Christoph, Critchley, David R., Barsukov, Igor L.
Publicado em 2013

Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation

Por Goult, Benjamin T, Bouaouina, Mohamed, Elliott, Paul R, Bate, Neil, Patel, Bipin, Gingras, Alexandre R, Grossmann, J Günter, Roberts, Gordon C K, Calderwood, David A, Critchley, David R, Barsukov, Igor L
Publicado em 2010

Vinculin controls talin engagement with the actomyosin machinery

Por Atherton, Paul, Stutchbury, Ben, Wang, De-Yao, Jethwa, Devina, Tsang, Ricky, Meiler-Rodriguez, Eugenia, Wang, Pengbo, Bate, Neil, Zent, Roy, Barsukov, Igor L., Goult, Benjamin T., Critchley, David R., Ballestrem, Christoph
Publicado no Nat Commun (2015)

Mechanism of the Ca(2+)-Dependent Interaction between S100A4 and Tail Fragments of Nonmuscle Myosin Heavy Chain IIA

Por Badyal, Sandip K., Basran, Jaswir, Bhanji, Nina, Kim, Ju Hwan, Chavda, Alap P., Jung, Hyun Suk, Craig, Roger, Elliott, Paul R., Irvine, Andrew F., Barsukov, Igor L., Kriajevska, Marina, Bagshaw, Clive R.
Publicado em 2011

The structure of the C-terminal actin-binding domain of talin

Por Gingras, Alexandre R, Bate, Neil, Goult, Benjamin T, Hazelwood, Larnele, Canestrelli, Ilona, Grossmann, J Günter, Liu, HongJun, Putz, Nicholas S M, Roberts, Gordon C K, Volkmann, Niels, Hanein, Dorit, Barsukov, Igor L, Critchley, David R
Publicado em 2008

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras

Por Lilja, Johanna, Zacharchenko, Thomas, Georgiadou, Maria, Jacquemet, Guillaume, De Franceschi, Nicola, Peuhu, Emilia, Hamidi, Hellyeh, Pouwels, Jeroen, Martens, Victoria, Nia, Fatemeh Hassani, Beifuss, Malte, Boeckers, Tobias, Kreienkamp, Hans-Juergen, Barsukov, Igor L, Ivaska, Johanna
Publicado no Nat Cell Biol (2017)

Asymmetric Mode of Ca(2+)-S100A4 Interaction with Nonmuscle Myosin IIA Generates Nanomolar Affinity Required for Filament Remodeling

Por Elliott, Paul R., Irvine, Andrew F., Jung, Hyun Suk, Tozawa, Kaeko, Pastok, Martyna W., Picone, Remigio, Badyal, Sandip K., Basran, Jaswir, Rudland, Philip S., Barraclough, Roger, Lian, Lu-Yun, Bagshaw, Clive R., Kriajevska, Marina, Barsukov, Igor L.
Publicado em 2012

Structural Determinants of Integrin Binding to the Talin Rod

Por Gingras, Alexandre R., Ziegler, Wolfgang H., Bobkov, Andrey A., Joyce, M. Gordon, Fasci, Domenico, Himmel, Mirko, Rothemund, Sven, Ritter, Anett, Grossmann, J. Günter, Patel, Bipin, Bate, Neil, Goult, Benjamin T., Emsley, Jonas, Barsukov, Igor L., Roberts, Gordon C. K., Liddington, Robert C., Ginsberg, Mark H., Critchley, David R.
Publicado em 2009