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Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation
Talin is a 270-kDa protein that activates integrins and couples them to cytoskeletal actin. Talin contains an N-terminal FERM domain comprised of F1, F2 and F3 domains, but it is atypical in that F1 contains a large insert and is preceded by an extra domain F0. Although F3 contains the binding site...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2845276/ https://ncbi.nlm.nih.gov/pubmed/20150896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.4 |
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