Structural Determinants of Integrin Binding to the Talin Rod

The adaptor protein talin serves both to activate the integrin family of cell adhesion molecules and to couple integrins to the actin cytoskeleton. Integrin activation has been shown to involve binding of the talin FERM domain to membrane proximal sequences in the cytoplasmic domain of the integrin...

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Main Authors: Gingras, Alexandre R., Ziegler, Wolfgang H., Bobkov, Andrey A., Joyce, M. Gordon, Fasci, Domenico, Himmel, Mirko, Rothemund, Sven, Ritter, Anett, Grossmann, J. Günter, Patel, Bipin, Bate, Neil, Goult, Benjamin T., Emsley, Jonas, Barsukov, Igor L., Roberts, Gordon C. K., Liddington, Robert C., Ginsberg, Mark H., Critchley, David R.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2009
主題:
Protein Structure and Folding
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659244/
https://ncbi.nlm.nih.gov/pubmed/19176533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805937200
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