Structural Determinants of Integrin Binding to the Talin Rod

The adaptor protein talin serves both to activate the integrin family of cell adhesion molecules and to couple integrins to the actin cytoskeleton. Integrin activation has been shown to involve binding of the talin FERM domain to membrane proximal sequences in the cytoplasmic domain of the integrin...

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Autors principals: Gingras, Alexandre R., Ziegler, Wolfgang H., Bobkov, Andrey A., Joyce, M. Gordon, Fasci, Domenico, Himmel, Mirko, Rothemund, Sven, Ritter, Anett, Grossmann, J. Günter, Patel, Bipin, Bate, Neil, Goult, Benjamin T., Emsley, Jonas, Barsukov, Igor L., Roberts, Gordon C. K., Liddington, Robert C., Ginsberg, Mark H., Critchley, David R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Protein Structure and Folding
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659244/
https://ncbi.nlm.nih.gov/pubmed/19176533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805937200
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