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Control of High Affinity Interactions in the Talin C Terminus: HOW TALIN DOMAINS COORDINATE PROTEIN DYNAMICS IN CELL ADHESIONS

In cell-extracellular matrix junctions (focal adhesions), the cytoskeletal protein talin is central to the connection of integrins to the actin cytoskeleton. Talin is thought to mediate this connection via its two integrin, (at least) three actin, and several vinculin binding sites. The binding site...

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Detalhes bibliográficos
Main Authors: Himmel, Mirko, Ritter, Anett, Rothemund, Sven, Pauling, Björg V., Rottner, Klemens, Gingras, Alexandre R., Ziegler, Wolfgang H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679484/
https://ncbi.nlm.nih.gov/pubmed/19278997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900266200
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