Cell Adhesion-dependent Serine 85 Phosphorylation of Paxillin Modulates Focal Adhesion Formation and Haptotactic Migration via Association with the C-terminal Tail Domain of Talin

Integrin-mediated adhesion to extracellular matrix proteins is dynamically regulated during morphological changes and cell migration. Upon cell adhesion, protein-protein interactions among molecules at focal adhesions (FAs) play major roles in the regulation of cell morphogenesis and migration. Alth...

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Main Authors: Kwak, Tae Kyoung, Lee, Mi-Sook, Ryu, Jihye, Choi, Yoon-Ju, Kang, Minkyung, Jeong, Doyoung, Lee, Jung Weon
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431675/
https://ncbi.nlm.nih.gov/pubmed/22761432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.323360
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