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Paxillin Enables Attachment-independent Tyrosine Phosphorylation of Focal Adhesion Kinase and Transformation by RAS

Paxillin and HIC5 are closely related adapter proteins that regulate cell migration and are tyrosine-phosphorylated by focal adhesion kinase (FAK). Paxillin, HIC5, and FAK tyrosine phosphorylation increase upon cell attachment and decrease upon detachment from extracellular matrix. Unexpectedly, we...

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書誌詳細
主要な著者: Wade, Ramon, Brimer, Nicole, Lyons, Charles, Pol, Scott Vande
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207406/
https://ncbi.nlm.nih.gov/pubmed/21900245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.294504
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