LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex

Cell migration requires coordination between integrin-mediated cell adhesion to the extracellular matrix and force applied to adhesion sites. Talin plays a key role in coupling integrin receptors to the actomyosin contractile machinery, while deleted in liver cancer 1 (DLC1) is a Rho GAP that binds...

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Publicado en:Structure
Autores principales: Zacharchenko, Thomas, Qian, Xiaolan, Goult, Benjamin T., Jethwa, Devina, Almeida, Teresa B., Ballestrem, Christoph, Critchley, David R., Lowy, Douglas R., Barsukov, Igor L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938799/
https://ncbi.nlm.nih.gov/pubmed/27265849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.04.016
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