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DLC1 is the principal biologically-relevant down-regulated DLC family member in several cancers
The RHO family of RAS-related GTPases in tumors may be activated by reduced levels of RHO GTPase accelerating proteins (GAPs). One common mechanism is decreased expression of one or more members of the Deleted in Liver Cancer (DLC) family of Rho-GAPs, which comprises three closely related genes (DLC...
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| Publicado no: | Oncotarget |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5216712/ https://ncbi.nlm.nih.gov/pubmed/27174913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9266 |
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