CDK5 is a major regulator of the tumor suppressor DLC1

DLC1 is a tumor suppressor protein whose full activity depends on its presence at focal adhesions, its Rho–GTPase activating protein (Rho-GAP) function, and its ability to bind several ligands, including tensin and talin. However, the mechanisms that regulate and coordinate these activities remain p...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Tripathi, Brajendra K., Qian, Xiaolan, Mertins, Philipp, Wang, Dunrui, Papageorge, Alex G., Carr, Steven A., Lowy, Douglas R.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2014
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259810/
https://ncbi.nlm.nih.gov/pubmed/25452387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201405105
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