Induction of HLA-DP4-restricted anti-Survivin Th1 and Th2 responses using an artificial antigen-presenting cell

Por Tanaka, Makito, Butler, Marcus O., Ansén, Sascha, Imataki, Osamu, Berezovskaya, Alla, Nadler, Lee M., Hirano, Naoto
Publicado em 2011

Dissociation of its opposing immunologic effects is critical for the optimization of anti-tumor CD8(+) T cell responses induced by IL-21

Por Ansén, Sascha, Butler, Marcus O., Berezovskaya, Alla, Murray, Andrew P., Stevenson, Kristen, Nadler, Lee M., Hirano, Naoto
Publicado em 2008

Identification of an immunogenic CD8(+) T-cell epitope derived from γ-globin, a putative tumor-associated antigen for juvenile myelomonocytic leukemia

Por Hirano, Naoto, Butler, Marcus O., Xia, Zhinan, Berezovskaya, Alla, Murray, Andrew P., Ansén, Sascha, Kojima, Seiji, Nadler, Lee M.
Publicado em 2006

Engagement of CD83 ligand induces prolonged expansion of CD8(+) T cells and preferential enrichment for antigen specificity

Por Hirano, Naoto, Butler, Marcus O., Xia, Zhinan, Ansén, Sascha, von Bergwelt-Baildon, Michael S., Neuberg, Donna, Freeman, Gordon J., Nadler, Lee M.
Publicado em 2006

IL-21 can supplement suboptimal Lck-independent MAPK activation in a STAT-3-dependent manner in human CD8(+) T cells

Por Imataki, Osamu, Ansén, Sascha, Tanaka, Makito, Butler, Marcus O., Berezovskaya, Alla, Milstein, Matthew I., Kuzushima, Kiyotaka, Nadler, Lee M., Hirano, Naoto
Publicado em 2012

A panel of human cell-based artificial APC enables the expansion of long-lived antigen-specific CD4(+) T cells restricted by prevalent HLA-DR alleles

Por Butler, Marcus O., Ansén, Sascha, Tanaka, Makito, Imataki, Osamu, Berezovskaya, Alla, Mooney, Mary M., Metzler, Genita, Milstein, Matthew I., Nadler, Lee M., Hirano, Naoto
Publicado em 2010

Ex Vivo Expansion of Human CD8(+) T Cells Using Autologous CD4(+) T Cell Help

Por Butler, Marcus O., Imataki, Osamu, Yamashita, Yoshihiro, Tanaka, Makito, Ansén, Sascha, Berezovskaya, Alla, Metzler, Genita, Milstein, Matthew I., Mooney, Mary M., Murray, Andrew P., Mano, Hiroyuki, Nadler, Lee M., Hirano, Naoto
Publicado em 2012

PD-L1 expression in non-small cell lung cancer: Correlations with genetic alterations

Por Scheel, Andreas H., Ansén, Sascha, Schultheis, Anne M., Scheffler, Matthias, Fischer, Rieke N., Michels, Sebastian, Hellmich, Martin, George, Julie, Zander, Thomas, Brockmann, Michael, Stoelben, Erich, Groen, Harry, Timens, Wim, Perner, Sven, von Bergwelt-Baildon, Michael, Büttner, Reinhard, Wolf, Jürgen
Publicado no Oncoimmunology (2016)

Benchmarking of Mutation Diagnostics in Clinical Lung Cancer Specimens

Por Querings, Silvia, Altmüller, Janine, Ansén, Sascha, Zander, Thomas, Seidel, Danila, Gabler, Franziska, Peifer, Martin, Markert, Eva, Stemshorn, Kathryn, Timmermann, Bernd, Saal, Beate, Klose, Stefan, Ernestus, Karen, Scheffler, Matthias, Engel-Riedel, Walburga, Stoelben, Erich, Brambilla, Elisabeth, Wolf, Jürgen, Nürnberg, Peter, Thomas, Roman K.
Publicado em 2011

Definition of a fluorescence in-situ hybridization score identifies high- and low-level FGFR1 amplification types in squamous cell lung cancer

Por Schildhaus, Hans-Ulrich, Heukamp, Lukas C, Merkelbach-Bruse, Sabine, Riesner, Katharina, Schmitz, Katja, Binot, Elke, Paggen, Ellen, Albus, Kerstin, Schulte, Wolfgang, Ko, Yon-Dschun, Schlesinger, Andreas, Ansén, Sascha, Engel-Riedel, Walburga, Brockmann, Michael, Serke, Monika, Gerigk, Ulrich, Huss, Sebastian, Göke, Friederike, Perner, Sven, Hekmat, Khosro, Frank, Konrad F, Reiser, Marcel, Schnell, Roland, Bos, Marc, Mattonet, Christian, Sos, Martin, Stoelben, Erich, Wolf, Jürgen, Zander, Thomas, Buettner, Reinhard
Publicado em 2012

Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer

Por Sos, Martin L., Fischer, Stefanie, Ullrich, Roland, Peifer, Martin, Heuckmann, Johannes M., Koker, Mirjam, Heynck, Stefanie, Stückrath, Isabel, Weiss, Jonathan, Fischer, Florian, Michel, Kathrin, Goel, Aviva, Regales, Lucia, Politi, Katerina A., Perera, Samanthi, Getlik, Matthäus, Heukamp, Lukas C., Ansén, Sascha, Zander, Thomas, Beroukhim, Rameen, Kashkar, Hamid, Shokat, Kevan M., Sellers, William R., Rauh, Daniel, Orr, Christine, Hoeflich, Klaus P., Friedman, Lori, Wong, Kwok-Kin, Pao, William, Thomas, Roman K.
Publicado em 2009

Rationale for co-targeting IGF-1R and ALK in ALK fusion positive lung cancer

Por Lovly, Christine M., McDonald, Nerina T., Chen, Heidi, Ortiz-Cuaran, Sandra, Heukamp, Lukas C., Yan, Yingjun, Florin, Alexandra, Ozretić, Luka, Lim, Diana, Wang, Lu, Chen, Zhao, Chen, Xi, Lu, Pengcheng, Paik, Paul K., Shen, Ronglai, Jin, Hailing, Buettner, Reinhard, Ansén, Sascha, Perner, Sven, Brockmann, Michael, Bos, Marc, Wolf, Jürgen, Gardizi, Masyar, Wright, Gavin M., Solomon, Benjamin, Russell, Prudence A., Rogers, Toni-Maree, Suehara, Yoshiyuki, Red-Brewer, Monica, Tieu, Rudy, de Stanchina, Elisa, Wang, Qingguo, Zhao, Zhongming, Johnson, David H., Horn, Leora, Wong, Kwok-Kin, Thomas, Roman K., Ladanyi, Marc, Pao, William
Publicado em 2014

Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data

Por Fernandez-Cuesta, Lynnette, Sun, Ruping, Menon, Roopika, George, Julie, Lorenz, Susanne, Meza-Zepeda, Leonardo A, Peifer, Martin, Plenker, Dennis, Heuckmann, Johannes M, Leenders, Frauke, Zander, Thomas, Dahmen, Ilona, Koker, Mirjam, Schöttle, Jakob, Ullrich, Roland T, Altmüller, Janine, Becker, Christian, Nürnberg, Peter, Seidel, Henrik, Böhm, Diana, Göke, Friederike, Ansén, Sascha, Russell, Prudence A, Wright, Gavin M, Wainer, Zoe, Solomon, Benjamin, Petersen, Iver, Clement, Joachim H, Sänger, Jörg, Brustugun, Odd-Terje, Helland, Åslaug, Solberg, Steinar, Lund-Iversen, Marius, Buettner, Reinhard, Wolf, Jürgen, Brambilla, Elisabeth, Vingron, Martin, Perner, Sven, Haas, Stefan A, Thomas, Roman K
Publicado no Genome Biol (2015)

Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing

Por Imielinski, Marcin, Berger, Alice H., Hammerman, Peter S., Hernandez, Bryan, Pugh, Trevor J., Hodis, Eran, Cho, Jeonghee, Suh, James, Capelletti, Marzia, Sivachenko, Andrey, Sougnez, Carrie, Auclair, Daniel, Lawrence, Michael, Stojanov, Petar, Cibulskis, Kristian, Choi, Kyusam, de Waal, Luc, Sharifnia, Tanaz, Brooks, Angela, Greulich, Heidi, Banerji, Shantanu, Zander, Thomas, Seidel, Danila, Leenders, Frauke, Ansén, Sascha, Ludwig, Corinna, Engel-Riedel, Walburga, Stoelben, Erich, Wolf, Jürgen, Goparju, Chandra, Thompson, Kristin, Winckler, Wendy, Kwiatkowski, David, Johnson, Bruce E., Jänne, Pasi A., Miller, Vincent A., Pao, William, Travis, William D., Pass, Harvey, Gabriel, Stacey, Lander, Eric, Thomas, Roman K., Garraway, Levi A., Getz, Gad, Meyerson, Matthew
Publicado em 2012

Frequent mutations in chromatin-remodeling genes in pulmonary carcinoids

Por Fernandez-Cuesta, Lynnette, Peifer, Martin, Lu, Xin, Sun, Ruping, Ozretić, Luka, Seidal, Danila, Zander, Thomas, Leenders, Frauke, George, Julie, Müller, Christian, Dahmen, Ilona, Pinther, Berit, Bosco, Graziella, Konrad, Kathryn, Altmüller, Janine, Nürnberg, Peter, Achter, Viktor, Lang, Ulrich, Schneider, Peter M, Bogus, Magdalena, Soltermann, Alex, Brustugun, Odd Terje, Helland, Åslaug, Solberg, Steinar, Lund-Iversen, Marius, Ansén, Sascha, Stoelben, Erich, Wright, Gavin M., Russell, Prudence, Wainer, Zoe, Solomon, Benjamin, Field, John K, Hyde, Russell, Davies, Michael PA., Heukamp, Lukas C, Petersen, Iver, Perner, Sven, Lovly, Christine, Cappuzzo, Federico, Travis, William D, Wolf, Jürgen, Vingron, Martin, Brambilla, Elisabeth, Haas, Stefan A., Buettner, Reinhard, Thomas, Roman K
Publicado em 2014

Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer

Por Hammerman, Peter S, Sos, Martin L, Ramos, Alex H, Xu, Chunxiao, Dutt, Amit, Zhou, Wenjun, Brace, Lear E, Woods, Brittany A, Lin, Wenchu, Zhang, Jianming, Deng, Xianming, Lim, Sang Min, Heynck, Stefanie, Peifer, Martin, Simard, Jeffrey R, Lawrence, Michael S, Onofrio, Robert C, Salvesen, Helga B, Seidel, Danila, Zander, Thomas, Heuckmann, Johannes M, Soltermann, Alex, Moch, Holger, Koker, Mirjam, Leenders, Frauke, Gabler, Franziska, Querings, Silvia, Ansén, Sascha, Brambilla, Elisabeth, Brambilla, Christian, Lorimier, Philippe, Brustugun, Odd Terje, Helland, Åslaug, Petersen, Iver, Clement, Joachim H, Groen, Harry, Timens, Wim, Sietsma, Hannie, Stoelben, Erich, Wolf, Jürgen, Beer, David G, Tsao, Ming Sound, Hanna, Megan, Hatton, Charles, Eck, Michael J, Janne, Pasi A, Johnson, Bruce E, Winckler, Wendy, Greulich, Heidi, Bass, Adam J, Cho, Jeonghee, Rauh, Daniel, Gray, Nathanael S, Wong, Kwok-Kin, Haura, Eric B, Thomas, Roman K, Meyerson, Matthew
Publicado em 2011

Frequent and Focal FGFR1 Amplification Associates With Therapeutically Tractable FGFR1 Dependency in Squamous-cell Lung Cancer

Por Weiss, Jonathan, Sos, Martin L., Seidel, Danila, Peifer, Martin, Zander, Thomas, Heuckmann, Johannes M., Ullrich, Roland T., Menon, Roopika, Maier, Sebastian, Soltermann, Alex, Moch, Holger, Wagener, Patrick, Fischer, Florian, Heynck, Stefanie, Koker, Mirjam, Schöttle, Jakob, Leenders, Frauke, Gabler, Franziska, Dabow, Ines, Querings, Silvia, Heukamp, Lukas C., Balke-Want, Hyatt, Ansén, Sascha, Rauh, Daniel, Baessmann, Ingelore, Altmüller, Janine, Wainer, Zoe, Conron, Matthew, Wright, Gavin, Russell, Prudence, Solomon, Ben, Brambilla, Elisabeth, Brambilla, Christian, Lorimier, Philippe, Sollberg, Steinar, Brustugun, Odd Terje, Engel-Riedel, Walburga, Ludwig, Corinna, Petersen, Iver, Sänger, Jörg, Clement, Joachim, Groen, Harry, Timens, Wim, Sietsma, Hannie, Thunnissen, Erik, Smit, Egbert, Heideman, Daniëlle, Cappuzzo, Federico, Ligorio, Claudia, Damiani, Stefania, Hallek, Michael, Beroukhim, Rameen, Pao, William, Klebl, Bert, Baumann, Matthias, Buettner, Reinhard, Ernestus, Karen, Stoelben, Erich, Wolf, Jürgen, Nürnberg, Peter, Perner, Sven, Thomas, Roman K.
Publicado em 2010

Integrative genome analyses identify key somatic driver mutations of small cell lung cancer

Por Peifer, Martin, Fernández-Cuesta, Lynnette, Sos, Martin L, George, Julie, Seidel, Danila, Kasper, Lawryn H, Plenker, Dennis, Leenders, Frauke, Sun, Ruping, Zander, Thomas, Menon, Roopika, Koker, Mirjam, Dahmen, Ilona, Müller, Christian, Di Cerbo, Vincenzo, Schildhaus, Hans-Ulrich, Altmüller, Janine, Baessmann, Ingelore, Becker, Christian, de Wilde, Bram, Vandesompele, Jo, Böhm, Diana, Ansén, Sascha, Gabler, Franziska, Wilkening, Ines, Heynck, Stefanie, Heuckmann, Johannes M, Lu, Xin, Carter, Scott L, Cibulskis, Kristian, Banerji, Shantanu, Getz, Gad, Park, Kwon-Sik, Rauh, Daniel, Grütter, Christian, Fischer, Matthias, Pasqualucci, Laura, Wright, Gavin, Wainer, Zoe, Russell, Prudence, Petersen, Iver, Chen, Yuan, Stoelben, Erich, Ludwig, Corinna, Schnabel, Philipp, Hoffmann, Hans, Muley, Thomas, Brockmann, Michael, Engel-Riedel, Walburga, Muscarella, Lucia A, Fazio, Vito M, Groen, Harry, Timens, Wim, Sietsma, Hannie, Thunnissen, Erik, Smit, Egbert, Heideman, Daniëlle AM, Snijders, Peter JF, Cappuzzo, Federico, Ligorio, Claudia, Damiani, Stefania, Field, John, Solberg, Steinar, Brustugun, Odd Terje, Lund-Iversen, Marius, Sänger, Jörg, Clement, Joachim H, Soltermann, Alex, Moch, Holger, Weder, Walter, Solomon, Benjamin, Soria, Jean-Charles, Validire, Pierre, Besse, Benjamin, Brambilla, Elisabeth, Brambilla, Christian, Lantuejoul, Sylvie, Lorimier, Philippe, Schneider, Peter M, Hallek, Michael, Pao, William, Meyerson, Matthew, Sage, Julien, Shendure, Jay, Schneider, Robert, Büttner, Reinhard, Wolf, Jürgen, Nürnberg, Peter, Perner, Sven, Heukamp, Lukas C, Brindle, Paul K, Haas, Stefan, Thomas, Roman K
Publicado no Nat Genet (2012)

Comprehensive genomic profiles of small cell lung cancer

Por George, Julie, Lim, Jing Shan, Jang, Se Jin, Cun, Yupeng, Ozretić, Luka, Kong, Gu, Leenders, Frauke, Lu, Xin, Fernández-Cuesta, Lynnette, Bosco, Graziella, Müller, Christian, Dahmen, Ilona, Jahchan, Nadine S., Park, Kwon-Sik, Yang, Dian, Karnezis, Anthony N., Vaka, Dedeepya, Torres, Angela, Wang, Maia Segura, Korbel, Jan O., Menon, Roopika, Chun, Sung-Min, Kim, Deokhoon, Wilkerson, Matt, Hayes, Neil, Engelmann, David, Pützer, Brigitte, Bos, Marc, Michels, Sebastian, Vlasic, Ignacija, Seidel, Danila, Pinther, Berit, Schaub, Philipp, Becker, Christian, Altmüller, Janine, Yokota, Jun, Kohno, Takashi, Iwakawa, Reika, Tsuta, Koji, Noguchi, Masayuki, Muley, Thomas, Hoffmann, Hans, Schnabel, Philipp A., Petersen, Iver, Chen, Yuan, Soltermann, Alex, Tischler, Verena, Choi, Chang-min, Kim, Yong-Hee, Massion, Pierre P., Zou, Yong, Jovanovic, Dragana, Kontic, Milica, Wright, Gavin M., Russell, Prudence A., Solomon, Benjamin, Koch, Ina, Lindner, Michael, Muscarella, Lucia A., la Torre, Annamaria, Field, John K., Jakopovic, Marko, Knezevic, Jelena, Castaños-Vélez, Esmeralda, Roz, Luca, Pastorino, Ugo, Brustugun, Odd-Terje, Lund-Iversen, Marius, Thunnissen, Erik, Köhler, Jens, Schuler, Martin, Botling, Johan, Sandelin, Martin, Sanchez-Cespedes, Montserrat, Salvesen, Helga B., Achter, Viktor, Lang, Ulrich, Bogus, Magdalena, Schneider, Peter M., Zander, Thomas, Ansén, Sascha, Hallek, Michael, Wolf, Jürgen, Vingron, Martin, Yatabe, Yasushi, Travis, William D., Nürnberg, Peter, Reinhardt, Christian, Perner, Sven, Heukamp, Lukas, Büttner, Reinhard, Haas, Stefan A., Brambilla, Elisabeth, Peifer, Martin, Sage, Julien, Thomas, Roman K.
Publicado no Nature (2015)