FGFR1 amplifications in squamous cell carcinomas of the lung: diagnostic and therapeutic implications

Por Schildhaus, Hans-Ulrich, Nogova, Lucia, Wolf, Jürgen, Buettner, Reinhard
Publicado no Transl Lung Cancer Res (2013)

Activated RET and ROS: two new driver mutations in lung adenocarcinoma

Por Bos, Marc, Gardizi, Masyar, Schildhaus, Hans-Ulrich, Buettner, Reinhard, Wolf, Juergen
Publicado no Transl Lung Cancer Res (2013)

Spindle cell embryonal rhabdomyosarcoma of the prostate in an adult patient – case report and review of clinicopathological features

Por Schildhaus, Hans-Ulrich, Lokka, Suvi, Fenner, Werner, Küster, Jens, Kühnle, Ingrid, Heinmöller, Ernst
Publicado no Diagn Pathol (2016)

Challenging dedifferentiated liposarcoma identified by MDM2-amplification, a report of two cases

Por Lokka, Suvi, Scheel, Andreas H, Dango, Sebastian, Schmitz, Katja, Hesterberg, Rudolf, Rüschoff, Josef, Schildhaus, Hans-Ulrich
Publicado em 2014

Squamous Cell Carcinoma of the Pancreas in a Patient with Germline BRCA2 Mutation-Response to Neoadjuvant Radiochemotherapy

Por Schultheis, Anne M., Nguyen, Gia Phuong, Ortmann, Monika, Kruis, Wolfgang, Büttner, Reinhard, Schildhaus, Hans-Ulrich, Markiefka, Birgid
Publicado em 2014

The Merendino procedure following preoperative imatinib mesylate for locally advanced gastrointestinal stromal tumor of the esophagogastric junction

Por Staiger, Wilko I, Ronellenfitsch, Ulrich, Kaehler, Georg, Schildhaus, Hans Ulrich, Dimitrakopoulou-Strauss, Antonia, Schwarzbach, Matthias HM, Hohenberger, Peter
Publicado em 2008

Partial Response to First-Line Crizotinib in an Elderly Male Patient with ROS1 Translocation-Positive Lung Cancer

Por Overbeck, Tobias R., Schmitz, Katja, Engelke, Christoph, Sahlmann, Carsten-Oliver, Hugo, Sara, Kellner, Laura, Trümper, Lorenz, Schildhaus, Hans-Ulrich
Publicado no Case Rep Oncol (2016)

Ovarian-type epithelial tumours of the testis: immunohistochemical and molecular analysis of two serous borderline tumours of the testis

Por Bürger, Tobias, Schildhaus, Hans-Ulrich, Inniger, Reinhard, Hansen, Joachim, Mayer, Peter, Schweyer, Stefan, Radzun, Heinz Joachim, Ströbel, Philipp, Bremmer, Felix
Publicado no Diagn Pathol (2015)

qPCR in gastrointestinal stromal tumors: Evaluation of reference genes and expression analysis of KIT and the alternative receptor tyrosine kinases FLT3, CSF1-R, PDGFRB, MET and AX...

Por Fassunke, Jana, Blum, Marie-Christine, Schildhaus, Hans-Ulrich, Zapatka, Marc, Brors, Benedikt, Künstlinger, Helen, Büttner, Reinhard, Wardelmann, Eva, Merkelbach-Bruse, Sabine
Publicado em 2010

EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy

Por Holtkamp, Nikola, Malzer, Elke, Zietsch, Jan, Okuducu, Ali Fuat, Mucha, Jana, Mawrin, Christian, Mautner, Victor-F., Schildhaus, Hans-Ulrich, von Deimling, Andreas
Publicado em 2008

c-myc copy number gain is a powerful prognosticator of disease outcome in cervical dysplasia

Por Kübler, Kirsten, Heinenberg, Sally, Rudlowski, Christian, Keyver-Paik, Mignon-Denise, Abramian, Alina, Merkelbach-Bruse, Sabine, Büttner, Reinhard, Kuhn, Walther, Schildhaus, Hans-Ulrich
Publicado no Oncotarget (2014)

Comparison of high resolution melting analysis, pyrosequencing, next generation sequencing and immunohistochemistry to conventional Sanger sequencing for the detection of p.V600E a...

Por Ihle, Michaela Angelika, Fassunke, Jana, König, Katharina, Grünewald, Inga, Schlaak, Max, Kreuzberg, Nicole, Tietze, Lothar, Schildhaus, Hans-Ulrich, Büttner, Reinhard, Merkelbach-Bruse, Sabine
Publicado em 2014

FGFR2 is overexpressed in myxoid liposarcoma and inhibition of FGFR signaling impairs tumor growth in vitro

Por Künstlinger, Helen, Fassunke, Jana, Schildhaus, Hans-Ulrich, Brors, Benedikt, Heydt, Carina, Ihle, Michaela Angelika, Mechtersheimer, Gunhild, Wardelmann, Eva, Büttner, Reinhard, Merkelbach-Bruse, Sabine
Publicado no Oncotarget (2015)

Comparison of Pre-Analytical FFPE Sample Preparation Methods and Their Impact on Massively Parallel Sequencing in Routine Diagnostics

Por Heydt, Carina, Fassunke, Jana, Künstlinger, Helen, Ihle, Michaela Angelika, König, Katharina, Heukamp, Lukas Carl, Schildhaus, Hans-Ulrich, Odenthal, Margarete, Büttner, Reinhard, Merkelbach-Bruse, Sabine
Publicado em 2014

A subset of gastrointestinal stromal tumors previously regarded as wild-type tumors carries somatic activating mutations in KIT exon 8 (p.D419del)

Por Huss, Sebastian, Künstlinger, Helen, Wardelmann, Eva, Kleine, Michaela A, Binot, Elke, Merkelbach-Bruse, Sabine, Rüdiger, Thomas, Mittler, Jens, Hartmann, Wolfgang, Büttner, Reinhard, Schildhaus, Hans-Ulrich
Publicado em 2013

MET Gene Copy Number Alterations and Expression of MET and Hepatocyte Growth Factor Are Potential Biomarkers in Angiosarcomas and Undifferentiated Pleomorphic Sarcomas

Por Schmitz, Katja, Koeppen, Hartmut, Binot, Elke, Fassunke, Jana, Künstlinger, Helen, Ihle, Michaela A., Heydt, Carina, Wardelmann, Eva, Büttner, Reinhard, Merkelbach-Bruse, Sabine, Rüschoff, Josef, Schildhaus, Hans-Ulrich
Publicado no PLoS One (2015)

Massively parallel sequencing fails to detect minor resistant subclones in tissue samples prior to tyrosine kinase inhibitor therapy

Por Heydt, Carina, Kumm, Niklas, Fassunke, Jana, Künstlinger, Helen, Ihle, Michaela Angelika, Scheel, Andreas, Schildhaus, Hans-Ulrich, Haller, Florian, Büttner, Reinhard, Odenthal, Margarete, Wardelmann, Eva, Merkelbach-Bruse, Sabine
Publicado no BMC Cancer (2015)

Pitfalls in mutational testing and reporting of common KIT and PDGFRA mutations in gastrointestinal stromal tumors

Por Merkelbach-Bruse, Sabine, Dietmaier, Wolfgang, Füzesi, Laszlo, Gaumann, Andreas, Haller, Florian, Kitz, Julia, Krohn, Antje, Mechtersheimer, Gunhild, Penzel, Roland, Schildhaus, Hans-Ulrich, Schneider-Stock, Regine, Simon, Ronald, Wardelmann, Eva
Publicado em 2010

Heterogeneity of KRAS Mutation Status in Rectal Cancer

Por Jo, Peter, König, Alexander, Schirmer, Markus, Kitz, Julia, Conradi, Lena-Christin, Azizian, Azadeh, Bernhardt, Markus, Wolff, Hendrik A., Grade, Marian, Ghadimi, Michael, Ströbel, Philipp, Schildhaus, Hans-Ulrich, Gaedcke, Jochen
Publicado no PLoS One (2016)

HR23b expression is a potential predictive biomarker for HDAC inhibitor treatment in mesenchymal tumours and is associated with response to vorinostat

Por Angelika Ihle, Michaela, Merkelbach‐Bruse, Sabine, Hartmann, Wolfgang, Bauer, Sebastian, Ratner, Nancy, Sonobe, Hiroshi, Nishio, Jun, Larsson, Olle, Åman, Pierre, Pedeutour, Florence, Taguchi, Takahiro, Wardelmann, Eva, Buettner, Reinhard, Schildhaus, Hans‐Ulrich
Publicado no J Pathol Clin Res (2016)