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FGFR1 amplifications in squamous cell carcinomas of the lung: diagnostic and therapeutic implications

Fibroblast growth factor receptor 1 (FGFR1) is a type 4 receptor tyrosine kinase. The receptor and its ligands play an important role in development and physiology. However, constitutive activation of FGFR1 by gene amplification, translocation or mutation is associated with various malignancies as,...

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Publicat a:Transl Lung Cancer Res
Autors principals: Schildhaus, Hans-Ulrich, Nogova, Lucia, Wolf, Jürgen, Buettner, Reinhard
Format: Artigo
Idioma:Inglês
Publicat: Pioneer Bioscience Publishing Company 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369858/
https://ncbi.nlm.nih.gov/pubmed/25806220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-6751.2013.03.03
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