EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy

Malignant peripheral nerve sheath tumors (MPNSTs) are sarcomas with poor prognosis and limited treatment options. Evidence for a role of epidermal growth factor receptor (EGFR) and receptor tyrosine kinase erbB2 in MPNSTs led us to systematically study these potential therapeutic targets in a larger...

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Hlavní autoři: Holtkamp, Nikola, Malzer, Elke, Zietsch, Jan, Okuducu, Ali Fuat, Mucha, Jana, Mawrin, Christian, Mautner, Victor-F., Schildhaus, Hans-Ulrich, von Deimling, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: Duke University Press 2008
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719009/
https://ncbi.nlm.nih.gov/pubmed/18650488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-053
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