EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy

Malignant peripheral nerve sheath tumors (MPNSTs) are sarcomas with poor prognosis and limited treatment options. Evidence for a role of epidermal growth factor receptor (EGFR) and receptor tyrosine kinase erbB2 in MPNSTs led us to systematically study these potential therapeutic targets in a larger...

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Detalhes bibliográficos
Main Authors: Holtkamp, Nikola, Malzer, Elke, Zietsch, Jan, Okuducu, Ali Fuat, Mucha, Jana, Mawrin, Christian, Mautner, Victor-F., Schildhaus, Hans-Ulrich, von Deimling, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Duke University Press 2008
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719009/
https://ncbi.nlm.nih.gov/pubmed/18650488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-053
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