EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy

Malignant peripheral nerve sheath tumors (MPNSTs) are sarcomas with poor prognosis and limited treatment options. Evidence for a role of epidermal growth factor receptor (EGFR) and receptor tyrosine kinase erbB2 in MPNSTs led us to systematically study these potential therapeutic targets in a larger...

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Bibliographic Details
Main Authors: Holtkamp, Nikola, Malzer, Elke, Zietsch, Jan, Okuducu, Ali Fuat, Mucha, Jana, Mawrin, Christian, Mautner, Victor-F., Schildhaus, Hans-Ulrich, von Deimling, Andreas
Format: Artigo
Language:Inglês
Published: Duke University Press 2008
Subjects:
Basic and Translational Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719009/
https://ncbi.nlm.nih.gov/pubmed/18650488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-053
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