Engagement of CD83 ligand induces prolonged expansion of CD8(+) T cells and preferential enrichment for antigen specificity

Following T-cell receptor and CD28 signaling, CD8(+) T cells express a receptor for CD83, a molecule up-regulated on functionally mature dendritic cells. Although this expression pattern suggests that CD83 is involved in adaptive immunity, little is known about its function in the periphery, and the...

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Detalhes bibliográficos
Main Authors: Hirano, Naoto, Butler, Marcus O., Xia, Zhinan, Ansén, Sascha, von Bergwelt-Baildon, Michael S., Neuberg, Donna, Freeman, Gordon J., Nadler, Lee M.
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895397/
https://ncbi.nlm.nih.gov/pubmed/16239433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-05-2073
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