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Identification of an immunogenic CD8(+) T-cell epitope derived from γ-globin, a putative tumor-associated antigen for juvenile myelomonocytic leukemia

Juvenile myelomonocytic leukemia (JMML) is a rare clonal myeloproliferative disorder. Although allogeneic stem cell transplantation can induce long-term remissions, relapse rates remain high and innovative approaches are needed. Since donor lymphocyte infusions have clinical activity in JMML, T-cell...

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Autors principals: Hirano, Naoto, Butler, Marcus O., Xia, Zhinan, Berezovskaya, Alla, Murray, Andrew P., Ansén, Sascha, Kojima, Seiji, Nadler, Lee M.
Format: Artigo
Idioma:Inglês
Publicat: © 2006 by The American Society of Hematology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895581/
https://ncbi.nlm.nih.gov/pubmed/16778141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-017566
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