Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer

While genomically targeted therapies have improved outcomes for patients with lung adenocarcinoma, little is known about the genomic alterations which drive squamous cell lung cancer. Sanger sequencing of the tyrosine kinome identified mutations in the DDR2 kinase gene in 3.8% of squamous cell lung...

সম্পূর্ণ বিবরণ

সংরক্ষণ করুন:
গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Hammerman, Peter S, Sos, Martin L, Ramos, Alex H, Xu, Chunxiao, Dutt, Amit, Zhou, Wenjun, Brace, Lear E, Woods, Brittany A, Lin, Wenchu, Zhang, Jianming, Deng, Xianming, Lim, Sang Min, Heynck, Stefanie, Peifer, Martin, Simard, Jeffrey R, Lawrence, Michael S, Onofrio, Robert C, Salvesen, Helga B, Seidel, Danila, Zander, Thomas, Heuckmann, Johannes M, Soltermann, Alex, Moch, Holger, Koker, Mirjam, Leenders, Frauke, Gabler, Franziska, Querings, Silvia, Ansén, Sascha, Brambilla, Elisabeth, Brambilla, Christian, Lorimier, Philippe, Brustugun, Odd Terje, Helland, Åslaug, Petersen, Iver, Clement, Joachim H, Groen, Harry, Timens, Wim, Sietsma, Hannie, Stoelben, Erich, Wolf, Jürgen, Beer, David G, Tsao, Ming Sound, Hanna, Megan, Hatton, Charles, Eck, Michael J, Janne, Pasi A, Johnson, Bruce E, Winckler, Wendy, Greulich, Heidi, Bass, Adam J, Cho, Jeonghee, Rauh, Daniel, Gray, Nathanael S, Wong, Kwok-Kin, Haura, Eric B, Thomas, Roman K, Meyerson, Matthew
বিন্যাস: Artigo
ভাষা:Inglês
প্রকাশিত: 2011
বিষয়গুলি:
Article
অনলাইন ব্যবহার করুন:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274752/
https://ncbi.nlm.nih.gov/pubmed/22328973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8274.CD-11-0005
ট্যাগগুলো: ট্যাগ যুক্ত করুন
কোনো ট্যাগ নেই, প্রথমজন হিসাবে ট্যাগ করুন!

অনুরূপ উপাদানগুলি