Uncoupling the Warburg effect from cancer

Por Najafov, Ayaz, Alessi, Dario R.
Publicado em 2010

Kinase Drug Discovery – What’s Next in the Field?

Por Cohen, Philip, Alessi, Dario R.
Publicado em 2012

Novel role for the LKB1 pathway in controlling monocarboxylate fuel transporters

Por Filippi, Beatrice Maria, Alessi, Dario R.
Publicado em 2008

LKB1 and AMPK and the cancer-metabolism link - ten years after

Por Hardie, D Grahame, Alessi, Dario R
Publicado em 2013

Cancer, oncogenes and signal transduction

Por McManus, Edward J, Alessi, Dario R
Publicado em 2004

A meeting of minds: Overcoming roadblocks in the development of therapies for neurodegenerative disorders

Por Muqit, Miratul M K, Alessi, Dario R
Publicado em 2009

3′phosphoinositide-dependent kinase-1 is essential for ischemic preconditioning of the myocardium

Por Budas, Grant R., Sukhodub, Andrey, Alessi, Dario R., Jovanović, Aleksandar
Publicado em 2006

Deficiency of PDK1 in liver results in glucose intolerance, impairment of insulin-regulated gene expression and liver failure

Por Mora, Alfonso, Lipina, Christopher, Tronche, François, Sutherland, Calum, Alessi, Dario R.
Publicado em 2005

Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1.

Por Kimber, Wendy A, Deak, Maria, Prescott, Alan R, Alessi, Dario R
Publicado em 2003

The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases

Por Vitari, Alberto C., Deak, Maria, Morrice, Nick A., Alessi, Dario R.
Publicado em 2005

Characterization of TAE684 as a potent LRRK2 kinase inhibitor

Por Zhang, Jinwei, Deng, Xianming, Choi, Hwan Geun, Alessi, Dario R., Gray, Nathanael S.
Publicado em 2012

Role of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4)P(2) in regulating insulin sensitivity defined by knock-in analysis

Por Wullschleger, Stephan, Wasserman, David H., Gray, Alex, Sakamoto, Kei, Alessi, Dario R.
Publicado no Biochem J (2011)

The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB

Por Biondi, Ricardo M., Kieloch, Agnieszka, Currie, Richard A., Deak, Maria, Alessi, Dario R.
Publicado em 2001

Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability.

Por Boudeau, Jérôme, Deak, Maria, Lawlor, Margaret A, Morrice, Nick A, Alessi, Dario R
Publicado em 2003

How moderate changes in Akt T-loop phosphorylation impact on tumorigenesis and insulin resistance

Por Wullschleger, Stephan, Sakamoto, Kei, Johnstone, Lana, Duce, Suzanne, Fleming, Stewart, Alessi, Dario R.
Publicado em 2011

Critical role of the SPAK protein kinase CCT domain in controlling blood pressure

Por Zhang, Jinwei, Siew, Keith, Macartney, Thomas, O'Shaughnessy, Kevin M., Alessi, Dario R.
Publicado no Hum Mol Genet (2015)

Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase

Por Wang, Xuemin, Li, Wei, Williams, Michayla, Terada, Naohiro, Alessi, Dario R., Proud, Christopher G.
Publicado em 2001

Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrom...

Por Sapkota, Gopal P, Boudeau, Jérôme, Deak, Maria, Kieloch, Agnieszka, Morrice, Nick, Alessi, Dario R
Publicado em 2002

Structural and biochemical characterization of the KLHL3–WNK kinase interaction important in blood pressure regulation

Por Schumacher, Frances-Rose, Sorrell, Fiona J., Alessi, Dario R., Bullock, Alex N., Kurz, Thimo
Publicado em 2014

In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation

Por Collins, Barry J., Deak, Maria, Arthur, J.Simon C., Armit, Laura J., Alessi, Dario R.
Publicado em 2003