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Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability.
LKB1 is a widely expressed serine/threonine protein kinase that is mutated in the inherited Peutz-Jeghers cancer syndrome. Recent findings indicate that LKB1 functions as a tumour suppressor, but little is known regarding the detailed mechanism by which LKB1 regulates cell growth. In this study we h...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223241/ https://ncbi.nlm.nih.gov/pubmed/12489981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021813 |
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