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LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1
We recently demonstrated that the LKB1 tumour suppressor kinase, in complex with the pseudokinase STRAD and the scaffolding protein MO25, phosphorylates and activates AMP-activated protein kinase (AMPK). A total of 12 human kinases (NUAK1, NUAK2, BRSK1, BRSK2, QIK, QSK, SIK, MARK1, MARK2, MARK3, MAR...
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| Gepubliceerd in: | EMBO J |
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| Hoofdauteurs: | , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2004
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC381014/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14976552/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600110 |
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