LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

We recently demonstrated that the LKB1 tumour suppressor kinase, in complex with the pseudokinase STRAD and the scaffolding protein MO25, phosphorylates and activates AMP-activated protein kinase (AMPK). A total of 12 human kinases (NUAK1, NUAK2, BRSK1, BRSK2, QIK, QSK, SIK, MARK1, MARK2, MARK3, MAR...

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Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: Lizcano, Jose M, Göransson, Olga, Toth, Rachel, Deak, Maria, Morrice, Nick A, Boudeau, Jérôme, Hawley, Simon A, Udd, Lina, Mäkelä, Tomi P, Hardie, D Grahame, Alessi, Dario R
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2004
Teme:
Article
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC381014/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14976552/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600110
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