The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation

Recent work indicates that the LKB1 tumour suppressor protein kinase, which is mutated in Peutz–Jeghers cancer syndrome, phosphorylates and activates a group of protein kinases that are related to AMPK (AMP-activated protein kinase). Ten of the 14 AMPK-related protein kinases activated by LKB1, incl...

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Detalhes bibliográficos
Main Authors: Jaleel, Mahaboobi, Villa, Fabrizio, Deak, Maria, Toth, Rachel, Prescott, Alan R., van Aalten, Daan M. F., Alessi, Dario R.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383704/
https://ncbi.nlm.nih.gov/pubmed/16396636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051844
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