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LKB1 and AMPK and the cancer-metabolism link - ten years after

The identification of a complex containing the tumor suppressor LKB1 as the critical upstream kinase required for the activation of AMP-activated protein kinase (AMPK) by metabolic stress was reported in an article in Journal of Biology in 2003. This finding represented the first clear link between...

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Detalhes bibliográficos
Main Authors: Hardie, D Grahame, Alessi, Dario R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626889/
https://ncbi.nlm.nih.gov/pubmed/23587167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-11-36
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