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Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome.

Peutz-Jeghers syndrome is an inherited cancer syndrome, which results in a greatly increased risk of developing tumours in those affected. The causative gene encodes a nuclear-localized protein kinase, termed LKB1, which is predicted to function as a tumour suppressor. The mechanism by which LKB1 is...

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Sonraí Bibleagrafaíochta
Main Authors: Sapkota, Gopal P, Boudeau, Jérôme, Deak, Maria, Kieloch, Agnieszka, Morrice, Nick, Alessi, Dario R
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2002
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222410/
https://ncbi.nlm.nih.gov/pubmed/11853558
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