Germline and Somatic Mutations of the STK11/LKB1 Peutz-Jeghers Gene in Pancreatic and Biliary Cancers

Peutz-Jeghers syndrome (PJS) is an autosomal-dominant disorder characterized by hamartomatous polyps in the gastrointestinal tract and by pigmented macules of the lips, buccal mucosa, and digits. Less appreciated is the fact that PJS also predisposes patients to an increased risk of gastrointestinal...

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Detalhes bibliográficos
Main Authors: Su, Gloria H., Hruban, Ralph H., Bansal, Ravi K., Bova, G. Steven, Tang, David J., Shekher, Manu C., Westerman, Anne Marie, Entius, Mark M., Goggins, Michael, Yeo, Charles J., Kern, Scott E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 1999
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Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866632/
https://ncbi.nlm.nih.gov/pubmed/10362809
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