Germline and Somatic Mutations of the STK11/LKB1 Peutz-Jeghers Gene in Pancreatic and Biliary Cancers

Peutz-Jeghers syndrome (PJS) is an autosomal-dominant disorder characterized by hamartomatous polyps in the gastrointestinal tract and by pigmented macules of the lips, buccal mucosa, and digits. Less appreciated is the fact that PJS also predisposes patients to an increased risk of gastrointestinal...

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Autores principales: Su, Gloria H., Hruban, Ralph H., Bansal, Ravi K., Bova, G. Steven, Tang, David J., Shekher, Manu C., Westerman, Anne Marie, Entius, Mark M., Goggins, Michael, Yeo, Charles J., Kern, Scott E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 1999
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866632/
https://ncbi.nlm.nih.gov/pubmed/10362809
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