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In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation
PKB/Akt, S6K, SGK and RSK are mediators of responses triggered by insulin and growth factors and are activated following phosphorylation by 3-phosphoinositide-dependent protein kinase-1 (PDK1). To investigate the importance of a substrate-docking site in the kinase domain of PDK1 termed the ‘PIF-poc...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC175797/ https://ncbi.nlm.nih.gov/pubmed/12912918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg407 |
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