High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site

Podobne zapisy

• In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation
  od: Collins, Barry J., i wsp.
  Wydane: (2003)
• Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates
  od: Komander, David, i wsp.
  Wydane: (2004)
• Structural basis for UCN-01 (7-hydroxystaurosporine) specificity and PDK1 (3-phosphoinositide-dependent protein kinase-1) inhibition.
  od: Komander, David, i wsp.
  Wydane: (2003)
• The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB
  od: Biondi, Ricardo M., i wsp.
  Wydane: (2001)
• Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C–terminal residues of PKA
  od: Biondi, Ricardo M., i wsp.
  Wydane: (2000)