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A mostrar 1 - 20 resultados de 358 para a pesquisa '((eur j) OR (eun ji)) med chem', tempo de pesquisa: 0.27seg Refinar resultados
Tat-DJ-1 inhibits oxidative stress-mediated RINm5F cell death through suppression of NF-κB and MAPK activation
Inhibition of atherosclerosis-promoting microRNAs via targeted polyelectrolyte complex micelles

Corrigendum to “Synthesis and cytotoxic activity of novel Aring cleaved ursolic acid derivatives in human nonsmall cell lung cancer cells” [Eur. J. Med. Chem. 123 (2016) 317–331]
(E)-N'-Arylidene-2-(4-oxoquinazolin-4(3H)-yl) acetohydrazides: Synthesis and evaluation of antitumor cytotoxicity and caspase activation activity

Redox-based probes as tools to monitor oxidized protein tyrosine phosphatases in living cells
6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site

A Molecular Model for Cocaine Binding by the Immunotherapeutic Human/Mouse Chimeric Monoclonal Antibody 2E2
The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity

Design of a novel Thiophene Inhibitor of 15-Lipoxygenase-1 with both Anti-inflammatory and Neuroprotective Properties
An evaluation of Minor Groove Binders as anti-Trypanosoma brucei brucei therapeutics

Structure-Guided Design of Novel Trypanosoma brucei Methionyl-tRNA Synthetase Inhibitors
Biochemical evaluation of virtual screening methods reveals a cell-active inhibitor of the cancer-promoting phosphatases of regenerating liver

Synthesis and pharmacological evaluation of indole-based sigma receptor ligands
The relevance of K(i) calculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor

Synthesis and Biological Evaluation of Novel Hybrids of Highly Potent and Selective α4β2-Nicotinic Acetylcholine Receptor (nAChR) Partial Agonists
Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines

Facile synthesis of 1,2-dione-containing abietane analogues for the generation of human carboxylesterase inhibitors
Conformational study on cyclic melanocortin ligands and new insight into their binding mode at the MC4 receptor

Syntheses and in vitro evaluation of new S1PR1 compounds and initial evaluation of a lead F-18 radiotracer in rodents
Synthesis and Biological Evaluation of Isomeric Methoxy Substitutions on Anti-Cancer Indolyl-Pyridinyl-Propenones: Effects on Potency and Mode of Activity

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