A carregar...
Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines
Many cancers have the tumor suppressor p53 inactivated by mutation, making reactivation of mutant p53 with small molecules a promising strategy for the development of novel anticancer therapeutics. The oncogenic p53 mutation Y220C, which accounts for approximately 100,000 cancer cases per year, crea...
Na minha lista:
| Publicado no: | Eur J Med Chem |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Editions Scientifiques Elsevier
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5986712/ https://ncbi.nlm.nih.gov/pubmed/29702446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2018.04.035 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|