טוען...
An in silico algorithm for identifying stabilizing pockets in proteins: test case, the Y220C mutant of the p53 tumor suppressor protein
The p53 tumor suppressor protein performs a critical role in stimulating apoptosis and cell cycle arrest in response to oncogenic stress. The function of p53 can be compromised by mutation, leading to increased risk of cancer; approximately 50% of cancers are associated with mutations in the p53 gen...
שמור ב:
| הוצא לאור ב: | Protein Eng Des Sel |
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| Main Authors: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5001139/ https://ncbi.nlm.nih.gov/pubmed/27503952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzw035 |
| תגים: |
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